The main Express Scripts fax number for prior authorization is 1-877-251-5896, printed on its General Request Form. Medicare requests are split three ways: initial clinical coverage reviews go to 1-877-251-5896, administrative reviews and appeals to 1-877-328-9660, and clinical appeals to 1-877-852-4070. Home delivery prescriptions go to 800-837-0959, and only from a prescriber's office. If a form or letter shows a different number, use that one.

This guide lists each number with the Express Scripts or Evernorth page it came from, explains which plan type it belongs to, and covers what gets a fax sent back.

  • Verified numbers for prior authorization, Medicare reviews and appeals, and home delivery
  • The form decides the number: Express Scripts prints the fax line on each form
  • Prescription faxes come from prescribers, never from patients

Table of Contents

What Express Scripts accepts by fax

Express Scripts manages prescription benefits for employers, health plans, and Medicare plans, and runs Express Scripts Pharmacy for home delivery. Its prior authorization pages now sit on the site of its parent company, Evernorth; express-scripts.com links redirect there.

The usual fax traffic falls into three groups:

  • Prior authorization and exceptions for commercial plans, including step therapy and formulary exceptions.
  • Medicare coverage reviews and appeals, split into clinical and administrative tracks.
  • New prescriptions for home delivery, sent by the prescriber.

Express Scripts says it prefers electronic prior authorization, and it takes verbal requests at 800-753-2851 when ePA is not an option. Fax remains available through its forms.

Verified Express Scripts fax numbers

Verified November 2026:

Plan type What to fax Fax number Source
Commercial General Request prior authorization form (urgent: call 1-800-417-8164) 1-877-251-5896 General Request Form (PDF)
Commercial Benefit Coverage Request Form for $0 copay preventive drugs (clinical review) 1-877-328-9660 Prior Authorization Resources
Medicare Initial clinical coverage reviews 1-877-251-5896 Medicare Coverage Resources
Medicare Administrative coverage reviews and appeals 1-877-328-9660 Medicare Coverage Resources
Medicare Clinical appeals (redeterminations) 1-877-852-4070 Medicare Coverage Resources, Redetermination form (PDF)
Home delivery New Prescription fax form, from the prescriber's office (questions: 888-327-9791) 800-837-0959 New Prescription fax form (PDF)

Notes on the numbers:

  • State forms. Express Scripts posts state-specific prior authorization forms for states such as California, Colorado, Texas, and Massachusetts. Fax those to the number printed on each form.
  • Medicare phone lines. Express Scripts lists 1.844.374.7377 for clinical coverage reviews and appeals, and 1.800.413.1328 for administrative reviews. Its redetermination form also takes expedited appeals by phone at 1.800.935.6103.
  • Form age. The General Request Form carries a 2011 date code and the home delivery fax form has no date. Both are still hosted by Express Scripts, but a quick call to confirm the line costs less than a lost week.
  • Not every plan is the same. Some health plans that use Express Scripts publish their own forms and fax numbers. The plan's materials take priority.

The number on your form or letter wins

Express Scripts itself says the fax number appears on each prior authorization form, and that is the right habit for every request.

If a letter, form, or portal screen gives you a fax number for the case, use it. In particular:

  • A denial notice names the appeal route and deadline for that member's plan.
  • A state-specific form may route to a different unit than the general form.
  • A plan's own form for a drug managed by Express Scripts may print its own number.

A request sent to the wrong line does not arrive at the right team any faster. It arrives somewhere with no matching case, and the clock keeps running.

How to fax Express Scripts, step by step

  1. Check the plan type on the member ID card: Medicare or not.
  2. Download the right form from Express Scripts: general or state-specific prior authorization, Medicare coverage review or redetermination, or the New Prescription fax form.
  3. Complete every field, including the member ID, the drug and strength, the diagnosis, and the prescriber's NPI and secure fax number. A DEA number is required on the home delivery form for Schedule III to V drugs.
  4. Attach clinical support. Chart notes, drugs tried before, and test results. See our prior authorization guide for what reviewers need.
  5. Fax the home delivery form without a cover sheet. The form says no cover sheet is required, and signature stamps are not accepted.
  6. Keep the confirmation. The home delivery form calls the printed fax confirmation proof of receipt.

No fax machine at the practice? You can send a fax online for $2.99 with no subscription and no account. For home delivery prescriptions, Express Scripts only accepts faxes sent from a prescriber's office, so confirm that requirement before choosing a sending line.

Why Express Scripts faxes get sent back

The common causes are predictable:

  • Patient-sent prescriptions. The home delivery order form says faxes can only be accepted from a doctor's office.
  • Schedule II drugs by fax. Express Scripts cannot accept CII prescriptions by fax. Use e-prescribing.
  • Signature stamps on the prescription. A real signature is required.
  • Mixed tracks. A Medicare clinical appeal sent to the administrative line, or a commercial form sent to a Medicare number.
  • Thin documentation. A request with no chart notes often triggers a request for more information.
  • Urgent requests sent by fax only. The General Request Form tells prescribers to call 1-800-417-8164 for urgent requests.

Faxing Express Scripts comes down to the right form, the number printed on it, and a confirmation you keep.

Fax your Express Scripts documents now →

Frequently asked questions

What is the Express Scripts prior authorization fax number?

The Express Scripts General Request Form says to fax completed forms to 1-877-251-5896, and to call 1-800-417-8164 for urgent requests. State-specific forms may print a different number, so use the one on the form you are sending.

What is the Express Scripts Medicare appeals fax number?

Express Scripts lists 1-877-852-4070 for Medicare clinical appeals and 1-877-328-9660 for Medicare administrative coverage reviews and appeals. Initial Medicare clinical coverage reviews go to 1-877-251-5896.

How does a doctor fax a prescription to Express Scripts home delivery?

The prescriber faxes the New Prescription fax form to 800-837-0959, with no cover sheet, from the prescriber's office. Questions go to 888-327-9791. Schedule II prescriptions cannot be faxed; e-prescribing is the faster option.

Can I fax my own prescription to Express Scripts?

No. Express Scripts' home delivery order form says faxes can only be accepted from a doctor's office. Ask your prescriber to e-prescribe the prescription or fax it from the office.

Can I call Express Scripts instead of faxing a prior authorization?

Yes. Express Scripts takes verbal prior authorization requests at 800-753-2851 when electronic prior authorization is not possible. Electronic prior authorization is its preferred route.

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